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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
16.97
Human Site:
S378
Identified Species:
28.72
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S378
P
G
K
G
K
L
R
S
G
S
N
T
G
L
D
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S378
P
G
K
G
K
L
R
S
G
S
N
T
G
L
D
Rhesus Macaque
Macaca mulatta
P56490
532
60122
I402
N
G
C
H
K
V
K
I
M
P
C
S
F
P
V
Dog
Lupus familis
XP_541769
536
61594
S427
S
G
K
G
K
P
R
S
E
S
S
T
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S379
L
G
K
V
K
A
R
S
R
S
N
S
G
L
D
Rat
Rattus norvegicus
P31390
486
55674
S377
P
G
R
V
K
S
R
S
G
S
N
S
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
K380
P
E
S
Q
E
Q
P
K
G
P
S
G
L
G
G
Chicken
Gallus gallus
P30372
466
51547
T369
A
R
K
I
V
K
M
T
K
Q
P
A
K
K
K
Frog
Xenopus laevis
P30544
484
54107
A386
A
R
K
F
A
S
I
A
R
N
Q
V
R
K
K
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
P425
P
W
A
E
N
S
P
P
L
D
A
S
I
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
E418
K
A
S
K
K
K
R
E
K
S
S
A
K
K
E
Honey Bee
Apis mellifera
XP_395477
546
60788
S434
R
V
F
I
T
Q
K
S
N
V
A
S
Q
T
S
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
E392
R
R
K
L
N
V
R
E
K
S
R
Q
M
M
R
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
A540
P
S
R
A
I
P
K
A
Q
V
K
N
G
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
13.3
73.3
N.A.
66.6
73.3
N.A.
13.3
6.6
6.6
6.6
N.A.
20
6.6
20
13.3
P-Site Similarity:
100
100
33.3
80
N.A.
73.3
86.6
N.A.
26.6
13.3
20
13.3
N.A.
33.3
20
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
8
8
8
0
15
0
0
15
15
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
36
% D
% Glu:
0
8
0
8
8
0
0
15
8
0
0
0
0
0
8
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
43
0
22
0
0
0
0
29
0
0
8
43
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
8
0
8
8
0
0
0
0
8
0
0
% I
% Lys:
8
0
50
8
50
15
22
8
22
0
8
0
15
22
15
% K
% Leu:
8
0
0
8
0
15
0
0
8
0
0
0
8
36
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
0
% M
% Asn:
8
0
0
0
15
0
0
0
8
8
29
8
0
0
0
% N
% Pro:
43
0
0
0
0
15
15
8
0
15
8
0
0
8
0
% P
% Gln:
0
0
0
8
0
15
0
0
8
8
8
8
8
0
0
% Q
% Arg:
15
22
15
0
0
0
50
0
15
0
8
0
8
0
8
% R
% Ser:
8
8
15
0
0
22
0
43
0
50
22
36
0
0
8
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
22
0
8
0
% T
% Val:
0
8
0
15
8
15
0
0
0
15
0
8
0
0
15
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _